Wireless-enabled processor modules intended for communicating low-frequency phenomena (i.e., temperature, humidity, and ambient light) have been enabled to acquire and transmit multiple biological signals in real time, which has been achieved by using computationally efficient data acquisition, filtering, and compression algorithms, and interfacing the modules with biological interface hardware. The sensor modules can acquire and transmit raw biological signals at a rate of 32 kb/s, which is near the hardware limit of the modules. Furthermore, onboard signal processing enables one channel, sampled at a rate of 4000 samples/s at 12-bit resolution, to be compressed via adaptive differential-pulse-code modulation (ADPCM) and transmitted in real time. In addition, the sensors can be configured to filter and transmit individual time-referenced "spike" waveforms, or to transmit the spike height and width for alleviating network traffic and increasing battery life. The system is capable of acquiring eight channels of analog signals as well as data via an asynchronous serial connection. A back-end server archives the biological data received via networked gateway sensors, and hosts them to a client application that enables users to browse recorded data. The system also acquires, filters, and transmits oxygen saturation and pulse rate via a commercial-off-the-shelf interface board. The system architecture can be configured for performing real-time nonobtrusive biological monitoring of humans or rodents. This paper demonstrates that low-power, computational, and bandwidth-constrained wireless-enabled platforms can indeed be leveraged for wireless biosignal monitoring.

Small-form-factor, low-power wireless sensors—motes—are convenient to deploy, but lack the bandwidth to capture and transmit raw high-frequency data, such as human voices or neural signals, in real time. Local filtering can help, but we show that the right filter settings depend on changing ambient conditions and network effects such as congestion, which makes them dynamic and unpredictable. Mote collection systems for high-frequency data must support iteratively-tuned, deployment-specific filter settings as well as fast sampling.VANGO, our software system for high-frequency data collection, achieves these goals via integrated processing across network tiers. Bandwidth-limited sensor nodes reduce data in network but rely on microservers, which have greater computational capabilities and a wider scope of observation, to plan how. VANGO provides a cross-platform library for data transformation, measurement, and classification; a fast and low-jitter data acquisition system for motes; and a mechanism to control mote and microserver signal processing. With VANGO we have developed new applications: the first acoustic collection system for motes responsive to changing environmental conditions and user interests, and the first neural spike acquisition application capable of supporting a network of nodes.