Acute stroke demands prompt diagnosis and treatment to achieve optimal patient outcomes. However, the intricate and irregular nature of clinical data associated with acute stroke, particularly blood pressure (BP) measurements, presents substantial obstacles to effective visual analytics and decision-making. Through a year-long collaboration with experienced neurologists, we developed PhenoFlow, a visual analytics system that leverages the collaboration between human and Large Language Models (LLMs) to analyze the extensive and complex data of acute ischemic stroke patients. PhenoFlow pioneers an innovative workflow, where the LLM serves as a data wrangler while neurologists explore and supervise the output using visualizations and natural language interactions. This approach enables neurologists to focus more on decision-making with reduced cognitive load. To protect sensitive patient information, PhenoFlow only utilizes metadata to make inferences and synthesize executable codes, without accessing raw patient data. This ensures that the results are both reproducible and interpretable while maintaining patient privacy. The system incorporates a slice-and-wrap design that employs temporal folding to create an overlaid circular visualization. Combined with a linear bar graph, this design aids in exploring meaningful patterns within irregularly measured BP data. Through case studies, PhenoFlow has demonstrated its capability to support iterative analysis of extensive clinical datasets, reducing cognitive load and enabling neurologists to make well-informed decisions. Grounded in long-term collaboration with domain experts, our research demonstrates the potential of utilizing LLMs to tackle current challenges in data-driven clinical decision-making for acute ischemic stroke patients.

We present RCMVis, a visual analytics system to support interactive Route Choice Modeling analysis. It aims to model which characteristics of routes, such as distance and the number of traffic lights, affect travelers' route choice behaviors and how much they affect the choice during their trips. Through close collaboration with domain experts, we designed a visual analytics framework for Route Choice Modeling. The framework supports three interactive analysis stages: exploration, modeling, and reasoning. In the exploration stage, we help analysts interactively explore trip data from multiple origin-destination (OD) pairs and choose a subset of data they want to focus on. To this end, we provide coordinated multiple OD views with different foci that allow analysts to inspect, rank, and compare OD pairs in terms of their multidimensional attributes. In the modeling stage, we integrate a k-medoids clustering method and a path-size logit model into our system to enable analysts to model route choice behaviors from trips with support for feature selection, hyperparameter tuning, and model comparison. Finally, in the reasoning stage, we help analysts rationalize and refine the model by selectively inspecting the trips that strongly support the modeling result. For evaluation, we conducted a case study and interviews with domain experts. The domain experts discovered unexpected insights from numerous modeling results, allowing them to explore the hyperparameter space more effectively to gain better results. In addition, they gained OD- and road-level insights into which data mainly supported the modeling result, enabling further discussion of the model.

We present a communication support system, namely We-toon, that can bridge the webtoon writers and artists during sketch revision (i.e., character design and draft revision). In the highly iterative design process between the webtoon writers and artists, writers often have difficulties in precisely articulating their feedback on sketches owing to their lack of drawing proficiency. This drawback makes the writers rely on textual descriptions and reference images found using search engines, leading to indirect and inefficient communications. Inspired by a formative study, we designed We-toon to help writers revise webtoon sketches and effectively communicate with artists. Through a GAN-based image synthesis and manipulation, We-toon can interactively generate diverse reference images and synthesize them locally on any user-provided image. Our user study with 24 professional webtoon authors demonstrated that We-toon outperforms the traditional methods in terms of communication effectiveness and the writers’ satisfaction level related to the revised image.

We introduce Parallel Histogram Plot (PHP), a technique that overcomes the innate limitations of parallel coordinates plot (PCP) by attaching stacked-bar histograms with discrete color schemes to PCP. The color-coded histograms enable users to see an overview of the whole data without cluttering or scalability issues. Each rectangle in the PHP histograms is color coded according to the data ranking by a selected attribute. This color-coding scheme allows users to visually examine relationships between attributes, even between those that are displayed far apart, without repositioning or reordering axes. We adopt the Visual Information Seeking Mantra so that the polylines of the original PCP can be used to show details of a small number of selected items when the cluttering problem subsides. We also design interactions, such as a focus+context technique, to help users investigate small regions of interest in a space-efficient manner. We provide a real-world example in which PHP is effectively utilized compared with other visualizations, and we perform a controlled user study to evaluate the performance of PHP in helping users estimate the correlation between attributes. The results demonstrate that the performance of PHP was consistent in the estimation of correlations between two attributes regardless of the distance between them.

Git metadata contains rich information for developers to understand the overall context of a large software development project. Thus it can help new developers, managers, and testers understand the history of development without needing to dig into a large pile of unfamiliar source code. However, the current tools for Git visualization are not adequate to analyze and explore the metadata: They focus mainly on improving the usability of Git commands instead of on helping users understand the development history. Furthermore, they do not scale for large and complex Git commit graphs, which can play an important role in understanding the overall development history. In this paper, we present Githru, an interactive visual analytics system that enables developers to effectively understand the context of development history through the interactive exploration of Git metadata. We design an interactive visual encoding idiom to represent a large Git graph in a scalable manner while preserving the topological structures in the Git graph. To enable scalable exploration of a large Git commit graph, we propose novel techniques (graph reconstruction, clustering, and Context-Preserving Squash Merge (CSM) methods) to abstract a large-scale Git commit graph. Based on these Git commit graph abstraction techniques, Githru provides an interactive summary view to help users gain an overview of the development history and a comparison view in which users can compare different clusters of commits. The efficacy of Githru has been demonstrated by case studies with domain experts using real-world, in-house datasets from a large software development team at a major international IT company. A controlled user study with 12 developers comparing Githru to previous tools also confirms the effectiveness of Githru in terms of task completion time.

Audit logs are different from other software logs in that they record the most primitive events (i.e., system calls) in modern operating systems. Audit logs contain a detailed trace of an operating system, and thus have received great attention from security experts and system administrators. However, the complexity and size of audit logs, which increase in real time, have hindered analysts from understanding and analyzing them. In this paper, we present a novel visual analytics system, LongLine, which enables interactive visual analyses of large-scale audit logs. LongLine lowers the interpretation barrier of audit logs by employing human-understandable representations (e.g., file paths and commands) instead of abstract indicators of operating systems (e.g., file descriptors) as well as revealing the temporal patterns of the logs in a multi-scale fashion with meaningful granularity of time in mind (e.g., hourly, daily, and weekly). LongLine also streamlines comparative analysis between interesting subsets of logs, which is essential in detecting anomalous behaviors of systems. In addition, LongLine allows analysts to monitor the system state in a streaming fashion, keeping the latency between log creation and visualization less than one minute. Finally, we evaluate our system through a case study and a scenario analysis with security experts.

For interactive exploration of large-scale data, a preprocessing scheme (e.g., data cubes) has often been used to summarize the data and provide low-latency responses. However, such a scheme suffers from a prohibitively large amount of memory footprint as more dimensions are involved in querying, and a strong prerequisite that specific data structures have to be built from the data before querying. In this paper, we present SwiftTuna, a holistic system that streamlines the visual information seeking process on large-scale multidimensional data. SwiftTuna exploits an in-memory computing engine, Apache Spark, to achieve both scalability and performance without building precomputed data structures. We also present a novel interactive visualization technique, tailed charts, to facilitate large-scale multidimensional data exploration. To support responsive querying on large-scale data, SwiftTuna leverages an incremental processing approach, providing immediate low-fidelity responses (i.e., prompt responses) as well as delayed high-fidelity responses (i.e., incremental responses). Our performance evaluation demonstrates that SwiftTuna allows data exploration of a real-world dataset with four billion records while preserving the latency between incremental responses within a few seconds.

Charts are commonly used to present data in digital documents such as web pages, research papers, or presentation slides. When the underlying data is not available, it is necessary to extract the data from a chart image to utilize the data for further analysis or improve the chart for more accurate perception. In this paper, we present ChartSense, an interactive chart data extraction system. ChartSense first determines the chart type of a given chart image using a deep learning based classifier, and then extracts underlying data from the chart image using semi-automatic, interactive extraction algorithms optimized for each chart type. To evaluate chart type classification accuracy, we compared ChartSense with ReVision, a system with the state-of-the-art chart type classifier. We found that ChartSense was more accurate than ReVision. In addition, to evaluate data extraction performance, we conducted a user study, comparing ChartSense with WebPlotDigitizer, one of the most effective chart data extraction tools among publicly accessible ones. Our results showed that ChartSense was better than WebPlotDigitizer in terms of task completion time, error rate, and subjective preference.

We present an interactive visual analytics framework, GazeDx (abbr. of GazeDiagnosis), for the comparative analysis of gaze data from multiple readers examining volumetric images while integrating important contextual information with the gaze data. Gaze pattern comparison is essential to understanding how radiologists examine medical images, and to identifying factors influencing the examination. Most prior work depended upon comparisons with manually juxtaposed static images of gaze tracking results. Comparative gaze analysis with volumetric images is more challenging due to the additional cognitive load on 3D perception. A recent study proposed a visualization design based on direct volume rendering (DVR) for visualizing gaze patterns in volumetric images; however, effective and comprehensive gaze pattern comparison is still challenging due to a lack of interactive visualization tools for comparative gaze analysis. We take the challenge with GazeDx while integrating crucial contextual information such as pupil size and windowing into the analysis process for more in-depth and ecologically valid findings. Among the interactive visualization components in GazeDx, a context-embedded interactive scatterplot is especially designed to help users examine abstract gaze data in diverse contexts by embedding medical imaging representations well known to radiologists in it. We present the results from two case studies with two experienced radiologists, where they compared the gaze patterns of 14 radiologists reading two patients' volumetric CT images.

We present CloakingNote, a novel desktop interface for subtle writing. The main idea of CloakingNote is to misdirect observers' attention away from a real text by using a prominent decoy text. To assess the subtlety of CloakingNote, we conducted a subtlety test while varying the contrast ratio between the real text and its background. Our results demonstrated that the real text as well as the interface itself were subtle even when participants were aware that a writer might be engaged in suspicious activities. We also evaluated the feasibility of CloakingNote through a performance test and categorized the users' layout strategies.

In this paper, we present gaze-based bookmarking, EyeBookmark, to mitigate the deleterious effect of interruption during reading. The key idea of EyeBookmark is to provide a visual cue to help people decide where to resume reading. We design four highlighting methods and conduct a controlled user study with a proof-of-concept design to verify the usefulness of EyeBookmark. The user study demonstrates not only that participants preferred our highlighting methods but also that such highlighting methods significantly reduced the time taken to resume reading after interruption regardless of the difficulty of text.

BACKGROUND: Though cluster analysis has become a routine analytic task for bioinformatics research, it is still arduous for researchers to assess the quality of a clustering result. To select the best clustering method and its parameters for a dataset, researchers have to run multiple clustering algorithms and compare them. However, such a comparison task with multiple clustering results is cognitively demanding and laborious. RESULTS: In this paper, we present XCluSim, a visual analytics tool that enables users to interactively compare multiple clustering results based on the Visual Information Seeking Mantra. We build a taxonomy for categorizing existing techniques of clustering results visualization in terms of the Gestalt principles of grouping. Using the taxonomy, we choose the most appropriate interactive visualizations for presenting individual clustering results from different types of clustering algorithms. The efficacy of XCluSim is shown through case studies with a bioinformatician. CONCLUSIONS: Compared to other relevant tools, XCluSim enables users to compare multiple clustering results in a more scalable manner. Moreover, XCluSim supports diverse clustering algorithms and dedicated visualizations and interactions for different types of clustering results, allowing more effective exploration of details on demand. Through case studies with a bioinformatics researcher, we received positive feedback on the functionalities of XCluSim, including its ability to help identify stably clustered items across multiple clustering results.

In this paper, we explain the effect of lateral chromatic aberration (LCA) when reading information displayed on the screen and how it leads to misinterpretation of charts and values represented. Although the effect can be observed from natural scenes, we focus on LCA on modern display devices. We inform the readers of the significance of issues to those using corrective lenses, especially the high diopter eyeglasses. First, we explain the basics of LCA. Then, we present a user study to observe the effect on users' judgment when reading charts on display devices. We also introduce a prototype software-based correction method with promising results. Lastly, we suggest guidelines for information visualization designers to avoid such issues.

For irregularly measured time-series data, the measurement frequency or interval is as crucial information as measurements are. A well-known time-series visualization such as the line graph is good at showing an overall temporal pattern of change; however, it is not so effective in revealing the measurement frequency/interval while likely giving illusory confidence in values between measurements. In contrast, the bar graph is more effective in showing the frequency/interval, but less effective in showing an overall pattern than the line graph. We integrate the line graph and bar graph in a unified visualization model, called a ripple graph, to take the benefits of both of them with enhanced graphical integrity. Based on the ripple graph, we implemented an interactive time-series data visualization tool, called Stroscope, which facilitates multi-scale visualizations by providing users with a graphical widget to interactively control the integrated visualization model. We evaluated the visualization model (i.e., the ripple graph) through a controlled user study and Stroscope through long-term case studies with neurologists exploring large blood pressure measurement data of stroke patients. Results from our evaluations demonstrate that the ripple graph outperforms existing time-series visualizations, and that Stroscope has the efficacy and potential as an effective visual analysis tool for (irregularly) measured time-series data.

In this paper, we introduce LiveGantt as a novel interactive schedule visualization tool that helps users explore highly-concurrent large schedules from various perspectives. Although a Gantt chart is the most common approach to illustrate schedules, currently available Gantt chart visualization tools suffer from limited scalability and lack of interactions. LiveGantt is built with newly designed algorithms and interactions to improve conventional charts with better scalability, explorability, and reschedulability. It employs resource reordering and task aggregation to display the schedules in a scalable way. LiveGantt provides four coordinated views and filtering techniques to help users explore and interact with the schedules in more flexible ways. In addition, LiveGantt is equipped with an efficient rescheduler to allow users to instantaneously modify their schedules based on their scheduling experience in the fields. To assess the usefulness of the application of LiveGantt, we conducted a case study on manufacturing schedule data with four industrial engineering researchers. Participants not only grasped an overview of a schedule but also explored the schedule from multiple perspectives to make enhancements.

Gaze visualization has been used to understand the results from gaze tracking studies in a wide range of fields. In the medical field, diagnoses of medical images have been studied with gaze tracking technology to understand how radiologists read medical images. While prior work were mainly based on diagnosis with a single image, recent work focused on diagnosis with consecutive cross-sectional medical images acquired from preoperative computed tomography (CT) or magnetic resonance imaging (MRI). In the diagnosis, radiologists scroll through a stack of images to get a 3D cognition of organs and lesions. Thus, it is important to understand radiologists' gaze patterns three dimensionally across such contiguous cross-sectional images. However, little has been done to visualize more complicated gaze patterns from the contiguous cross-sectional medical images. To address this problem, we present an interactive 3D gaze visualization tool, GazeVis, where InfoVis and SciVis techniques are harmonized to show the abstract gaze data along with a realistic 3D rendering of the visual stimuli (i.e., organs and lesions). We present case studies with 12 radiologists who use GazeVis to investigate gaze patterns of their colleagues with different levels of expertise, providing empirical evidences about the competence of our gaze visualization system.

In this paper we present an interactive query interface called "TrapezoidBox" to support spatial proximity queries where users' degree of interest varies depending upon the degree of separation from the point of interest. Spatial proximity queries are commonly built in information seeking tasks especially on online maps. If not impossible, it is hard to formulate spatial proximity queries using existing dynamic query widgets such as range sliders. TrapezoidBox allows users to easily build spatial proximity queries by interactively adjusting a trapezoidal function. Our controlled user study results show that TrapezoidBox has several advantages over a baseline interface with range sliders.

Hierarchical structures with large fan-outs are hard to browse and understand. In the conventional node-link tree visualization, the screen quickly becomes overcrowded as users open nodes that have too many child nodes to fit in one screen. To address this problem, we propose two extensions to the conventional node-link tree visualization: a list view with a scrollbar and a multi-column interface. We compared them against the conventional tree visualization interface in a user study. Results show that users are able to browse and understand the tree structure faster with the multi-column interface than the other two interfaces. Overall, they also liked the multi-column better than others.

This study aimed to evaluate three image fidelity metrics of different computational principles--peak signal-to-noise ratio (PSNR), high-dynamic range visual difference predictor (HDR-VDP), and multiscale structural similarity (MS-SSIM)--in measuring the fidelity of JPEG2000 compressed abdomen computed tomography images from a viewpoint of visually lossless compression. Three hundred images with 0.67- or 5-mm section thickness were compressed to one of five compression ratios ranging from reversible compression to 15:1. The fidelity of each compressed image was measured by five radiologists' visual analyses (distinguishable or indistinguishable from the original) and the three metrics. The Spearman rank correlation coefficients of the PSNR, HDR-VDP, and MS-SSIM values with the number of readers responding as indistinguishable were 0.86, 0.94, and 0.86, respectively. Using the pooled readers' responses as the reference standard, the area under the receiver-operating-characteristic curve for the HDR-VDP (0.99) was significantly greater than that for the PSNR (0.95) (p < 0.001) and for the MS-SSIM (0.96) (p = 0.003), and there was no significant difference between the PSNR and MS-SSIM (p = 0.70). In measuring the image fidelity, the HDR-VDP outperforms the PSNR and MS-SSIM, and the MS-SSIM and PSNR are comparable.

Among the multifarious tag-clouding techniques, Wordle stands out to the community by providing an aesthetic layout, eliciting the emergence of the participatory culture and usage of tag-clouding in the artistic creations. In this paper, we introduce ManiWordle, a Wordle-based visualization tool that revamps interactions with the layout by supporting custom manipulations. ManiWordle allows people to manipulate typography, color, and composition not only for the layout as a whole, but also for the individual words, enabling them to have better control over the layout result. We first describe our design rationale along with the interaction techniques for tweaking the layout. We then present the results both from the preliminary usability study and from the comparative study between ManiWordle and Wordle. The results suggest that ManiWordle provides higher user satisfaction and an efficient method of creating the desired "art work," harnessing the power behind the ever-increasing popularity of Wordle.

Volume ray-casting with a higher order reconstruction filter and/or a higher sampling rate has been adopted in direct volume rendering frameworks to provide a smooth reconstruction of the volume scalar and/or to reduce artifacts when the combined frequency of the volume and transfer function is high. While it enables high-quality volume rendering, it cannot support interactive rendering due to its high computational cost. In this paper, we propose a fast high-quality volume ray-casting algorithm which effectively increases the sampling rate. While a ray traverses the volume, intensity values are uniformly reconstructed using a high-order convolution filter. Additional samplings, referred to as virtual samplings, are carried out within a ray segment from a cubic spline curve interpolating those uniformly reconstructed intensities. These virtual samplings are performed by evaluating the polynomial function of the cubic spline curve via simple arithmetic operations. The min max blocks are refined accordingly for accurate empty space skipping in the proposed method. Experimental results demonstrate that the proposed algorithm, also exploiting fast cubic texture filtering supported by programmable GPUs, offers renderings as good as a conventional ray-casting algorithm using high-order reconstruction filtering at the same sampling rate, while delivering 2.5x to 3.3x rendering speed-up.

A widespread use of high-throughput gene expression analysis techniques enabled the biomedical research community to share a huge body of gene expression datasets in many public databases on the web. However, current gene expression data repositories provide static representations of the data and support limited interactions. This hinders biologists from effectively exploring shared gene expression datasets. Responding to the growing need for better interfaces to improve the utility of the public datasets, we have designed and developed a new web-based visual interface entitled GeneShelf (http://bioinformatics.cnmcresearch.org/GeneShelf). It builds upon a zoomable grid display to represent two categorical dimensions. It also incorporates an augmented timeline with expandable time points that better shows multiple data values for the focused time point by embedding bar charts. We applied GeneShelf to one of the largest microarray datasets generated to study the progression and recovery process of injuries at the spinal cord of mice and rats. We present a case study and a preliminary qualitative user study with biologists to show the utility and usability of GeneShelf.

Scientific problem solving often involves concordance (or discordance) analysis among the result sets from different approaches. For example, different scientific analysis methods with the same samples often lead to different or even conflicting conclusions. To reach a more judicious conclusion, it is crucial to consider different perspectives by checking concordance among those result sets by different methods. In this paper, we present an interactive visualization tool called ConSet, where users can effectively examine relationships among multiple sets at once. ConSet provides an overview using an improved permutation matrix to enable users to easily identify relationships among sets with a large number of elements. Not only do we use a standard Venn diagram, we also introduce a new diagram called Fan diagram that allows users to compare two or three sets without any inconsistencies that may exist in Venn diagrams. A qualitative user study was conducted to evaluate how our tool works in comparison with a traditional set visualization tool based on a Venn diagram. We observed that ConSet enabled users to complete more tasks with fewer errors than the traditional interface did and most users preferred ConSet.