We introduce a novel multimodal framework for face recognition based on local attributes calculated from range and portrait image pairs. Gabor coefficients are computed at automatically detected landmark locations and combined with powerful anthropometric features defined in the form of geodesic and Euclidean distances between pairs of fiducial points. We make the pragmatic assumption that the 2-D and 3-D data is acquired passively (e.g., via stereo ranging) with perfect registration between the portrait data and the range data. Statistical learning approaches are evaluated independently to reduce the dimensionality of the 2-D and 3-D Gabor coefficients and the anthropometric distances. Three parallel face recognizers that result from applying the best performing statistical learning schemes are fused at the match score-level to construct a unified multimodal (2-D+3-D) face recognition system with boosted performance. Performance of the proposed algorithm is evaluated on a large public database of range and portrait image pairs and found to perform quite well.

Multicolor fluorescence in situ hybridization (M-FISH) techniques provide color karyotyping that allows simultaneous analysis of numerical and structural abnormalities of whole human chromosomes. Chromosomes are stained combinatorially in M-FISH. By analyzing the intensity combinations of each pixel, all chromosome pixels in an image are classified. Due to the overlap of excitation and emission spectra and the broad sensitivity of image sensors, the obtained images contain crosstalk between the color channels. The crosstalk complicates both visual and automatic image analysis and may eventually affect the classification accuracy in M-FISH. The removal of crosstalk is possible by finding the color compensation matrix, which quantifies the color spillover between channels. However, there exists no simple method of finding the color compensation matrix from multichannel fluorescence images whose specimens are combinatorially hybridized. In this paper, we present a method of calculating the color compensation matrix for multichannel fluorescence images whose specimens are combinatorially stained.

In this paper, we present a novel identity verification system based on Gabor features extracted from range (3D) representations of faces. Multiple landmarks (fiducials) on a face are automatically detected using these Gabor features. Once the landmarks are identified, the Gabor features on all fiducials of a face are concatenated to form a feature vector for that particular face. Linear discriminant analysis (LDA) is used to reduce the dimensionality of the feature vector while maximizing the discrimination power. These novel features were tested on 1196 range images. The same features were also extracted from portrait images, and the accuracies of both modalities were compared. A superior verification accuracy was obtained using the range data, and a highly competitive accuracy to that of other techniques in the literature was also obtained for the portrait data.

Multicolor fluorescence in situ hybridization (M-FISH) techniques provide color karyotyping that allows simultaneous analysis of numerical and structural abnormalities of whole human chromosomes. Chromosomes are stained combinatorially in M-FISH. By analyzing the intensity combinations of each pixel, all chromosome pixels in an image are classified. Often, the intensity distributions between different images are found to be considerably different and the difference becomes the source of misclassifications of the pixels. Improved pixel classification accuracy is the most important task to ensure the success of the M-FISH technique. In this paper, we introduce a new feature normalization method for M-FISH images that reduces the difference in the feature distributions among different images using the expectation maximization (EM) algorithm. We also introduce a new unsupervised, nonparametric classification method for M-FISH images. The performance of the classifier is as accurate as the maximum-likelihood classifier, whose accuracy also significantly improved after the EM normalization. We would expect that any classifier will likely produce an improved classification accuracy following the EM normalization. Since the developed classification method does not require training data, it is highly convenient when ground truth does not exist. A significant improvement was achieved on the pixel classification accuracy after the new feature normalization. Indeed, the overall pixel classification accuracy improved by 20% after EM normalization.

Interest in face recognition systems has increased significantly due to the emergence of significant commercial opportunities in surveillance and security applications. In this paper we propose a novel technique to extract features from 3D face representations. In this technique, first the nose tip is automatically located on the range image, then the range data from a hexagonal region of interest around this landmark is decomposed using Barycentric wavelet kernels. The dimensionality of the extracted coefficients at each resolution level is reduced using principal component analysis (PCA). These new features are tested on 206 range images, and a high classification accuracy is achieved using a small number of features. The obtained accuracy is competitive to that of other techniques in literature.

Biomedical specimens thicker than the microscope depth-of-field (DOF) produces images of limited quality where a part of the specimen is in focus and others out of focus. Even the best in-focus image always contains objects that are blurred. These blurred contents make the quantitative and accurate analysis of the specimen difficult. The problem can be remedied by extending the DOF of the imaging system. One way to achieve this is to apply digital image fusion, a software technique that combines multiple images into a carefully synthesized image. Another way, albeit more expensive, is to incorporate modification in the optical system. In this paper we describe an extended DOF method that is based on multiscale pointwise product (MPP) image fusion, and compare it with the state-of-the-art wavefront coding technique which involves optical modification. We show competitive performance of our method and contrast its pros and cons with those of the wavefront coding.

Multicolor fluorescence in-situ hybridization (M-FISH) technique provides color karyotyping that allows simultaneous analysis of numerical and structural abnormalities of whole human chromosomes. Currently available M-FISH systems exhibit misclassifications of multiple pixel regions that are often larger than the actual chromosomal rearrangement. This paper presents a novel unsupervised classification method based on fuzzy logic classification and a prior adjusted reclassification method. Utilizing the chromosome boundaries, the initial classification results improved significantly after the prior adjusted reclassification while keeping the translocations intact. This paper also presents a new segmentation method that combines both spectral and edge information. Ten M-FISH images from a publicly available database were used to test our methods. The segmentation accuracy was more than 98% on average.