High-dimensional mediation analysis (HMA) seeks to uncover complex causal mechanisms involving numerous mediators and plays a crucial role in scientific and social sciences. In this work, we introduce the Generative Adversarial High-dimensional Mediation Network (GAHMN), a novel, scalable structured generative framework designed for causal analysis in high-dimensional settings. GAHMN formulates mediation analysis as dual conditional generative blocks, explicitly capturing mediators' dual roles as outcomes influenced by treatments and as predictors affecting outcomes. Each block integrates a high-dimensional partially linear structure with multi-channel convolutional layers, promoting effective parameter sharing and enhanced representation learning. To induce sparsity and accurate mediator selection, GAHMN employs customized min-max optimization problems with L1 penalties on generator parameters, alongside specially designed optimization algorithms for efficient computation. Unlike existing benchmark methods relying on restrictive parametric assumptions or random-effect specifications, GAHMN flexibly captures heterogeneity, complex distributions, and inter-mediator correlations. With careful design, the computational complexity of GAHMN scales linearly with the number of mediators p, rather than quadratically as in conventional approaches. Theoretical results rigorously ensures estimation consistency, convergence rate, and accurate sparse recovery. GAHMN also serves as a structured generative causal modeling framework, extending to causal decomposition, structural equation modeling, and counterfactual policy evaluation. Extensive experiments confirm GAHMN's superior performance and robustness in synthetic and real-world scenarios.

Online learning methods are designed to establish timely predictive models for machine learning problems. The methods for online learning of nonlinear systems are usually developed in the reproducing kernel Hilbert space (RKHS) associated with Gaussian kernel in which the kernel bandwidth is manually selected and remains steady during the entire modeling process in most cases. This setting may make the learning model rigid and inappropriate for complex data streams. Since the bandwidth appears in a nonlinear term of the kernel model, it raises substantial challenges in the development of learning methods with an adaptive bandwidth. In this article, we propose a novel approach to address this important open issue. By a carefully casted linearization scheme, the nonlinear learning problem is reasonably transformed into a state feedback control problem for a series of controllable systems. Then, by employing optimal control techniques, an effective algorithm is developed, and the parameters in the learning model including kernel bandwidth can be efficiently updated in a real-time manner. By taking advantage of the particular structure of the Gaussian kernel model, a theoretical analysis on the convergence and rationality of the proposed method is also provided. Compared with the kernel algorithms with a fixed bandwidth, our novel learning framework can not only achieve adaptive learning results with a better prediction accuracy but also show performance that is more robust with a faster convergence speed. Encouraging numerical results are provided to demonstrate the advantages of our new method.