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William Newell

dblp:94/7022 · DBLP profile ↗
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2ranked-venue papers
1as first author
0since 2021 · last 2020
—ORCID · none

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 2 · 1 first-author

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
2 papers
Bioinformatics and computational biology · 100%

Topics — the 7 heaviest of 7, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › statistical genetics › post-GWAS analysis
causal gene identification
0.412020
The open targets post-GWAS analysis pipeline · Bioinform. 2020
Bioinformatics and computational biology
genomics
0.412020
The open targets post-GWAS analysis pipeline · Bioinform. 2020
Bioinformatics and computational biology › statistical genetics
post-GWAS analysis
0.412020
The open targets post-GWAS analysis pipeline · Bioinform. 2020
Bioinformatics and computational biology
drug discovery
0.112020
The open targets post-GWAS analysis pipeline · Bioinform. 2020
Bioinformatics and computational biology › drug discovery
target identification
0.112020
The open targets post-GWAS analysis pipeline · Bioinform. 2020
Bioinformatics and computational biology › statistical genetics
genetic mapping
0.011998
WEBMAP: radiation hybrid mapping on the WWW · Bioinform. 1998
Bioinformatics and computational biology › genomics › physical mapping
radiation hybrid mapping
0.011998
WEBMAP: radiation hybrid mapping on the WWW · Bioinform. 1998

Methods — techniques the papers use, named apart from their topics

eQTL analysis · 0.4data integration · 0.4chromatin interaction analysis · 0.4java applet interface · 0.0
YearPublicationVenuePosition
2020 The open targets post-GWAS analysis pipeline
abstract
MOTIVATION: Genome-wide association studies (GWAS) are a powerful method to detect even weak associations between variants and phenotypes; however, many of the identified associated variants are in non-coding regions, and presumably influence gene expression regulation. Identifying potential drug targets, i.e. causal protein-coding genes, therefore, requires crossing the genetics results with functional data. RESULTS: We present a novel data integration pipeline that analyses GWAS results in the light of experimental epigenetic and cis-regulatory datasets, such as ChIP-Seq, Promoter-Capture Hi-C or eQTL, and presents them in a single report, which can be used for inferring likely causal genes. This pipeline was then fed into an interactive data resource. AVAILABILITY AND IMPLEMENTATION: The analysis code is available at www.github.com/Ensembl/postgap and the interactive data browser at postgwas.opentargets.io.
Gareth Peat, Michael Nuhn, José Carlos Marugán, William Newell, Ian Dunham, Daniel R. Zerbino
Bioinform.5
1998 WEBMAP: radiation hybrid mapping on the WWW
abstract
SUMMARY: A Java interface to radiation hybrid (RH) mapping software is described which enables users to build and interactively refine RH maps over the web. AVAILABILITY: The Java applets described here are available on the internet at http://www.oxmol.com/biolib/webmap/.
William Newell, Philippe Sanseau, John Riley, Andrew Lyall
Bioinform.1