Abstract Summary: Clinical GeneOrganizer (CGO) is a novel windows-based archiving, organization and data mining software for the integration of gene expression profiling in clinical medicine. The program implements various user-friendly tools and extracts data for further statistical analysis. This software was written for Affymetrix GeneChip©*.txt files, but can also be used for any other microarray-derived data. The MS-SQL server version acts as a data mart and links microarray data with clinical parameters of any other existing database and therefore represents a valuable tool for combining gene expression analysis and clinical disease characteristics. Availability: The software is available free of charge at http://lambertlab.uams.edu Contact: [email protected] Supplementary information: A snapshot of detailed program-specific table relationships and information on other programs including various cancer gene expression profiles are available on above mentioned web site. * To whom correspondence should be addressed.