Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains relatively limited, typically supporting only single tasks, which has somewhat constrained the development of CAD technology. To address the above limitation, in this paper, we construct a multi-task liver dataset (LiMT) used for liver and tumor segmentation, multi-label lesion classification, and lesion detection based on arterial phase-enhanced computed tomography (CT), potentially providing an exploratory solution that is able to explore the correlation between tasks and does not need to worry about the heterogeneity between task-specific datasets during training. The dataset includes CT volumes from 150 different cases, comprising four types of liver diseases as well as normal cases. Each volume has been carefully annotated and calibrated by experienced clinicians. This public multi-task dataset may become a valuable resource for the medical imaging research community in the future. In addition, this paper not only provides relevant baseline experimental results but also reviews existing datasets and methods related to liver-related tasks.

Knowledge distillation transfers knowledge from the teacher model to the student one, significantly enhancing the capabilities of the student network. However, alleviating the information gap between the corresponding stages of the student and teacher during the distillation process poses a challenge. This challenge is particularly noticeable at deeper levels, where the limited capability of the student may result in capturing less information, thus leading to poor learning performance. To overcome this limitation, we introduce a novel multi-stage local feature distillation method, which leverages fused multiple feature maps named tutor to bridge the gap. Additionally, we have designed the Value Attention-Based Fusion module (Value-ABF) to enhance feature fusion reasonably. Compared with other distillation methods, our approach achieves comparable or even superior results and demonstrates better training efficiency on CIFAR-100 and COCO2017 datasets for tasks such as image classification, object detection, and instance segmentation.

Despite the substantial progress made by deep networks in the field of medical image segmentation, they generally require sufficient pixel-level annotated data for training. The scale of training data remains to be the main bottleneck to obtain a better deep segmentation model. Semi-supervised learning is an effective approach that alleviates the dependence on labeled data. However, most existing semi-supervised image segmentation methods usually do not generate high-quality pseudo labels to expand training dataset. In this paper, we propose a deep semi-supervised approach for liver CT image segmentation by expanding pseudo-labeling algorithm under the very low annotated-data paradigm. Specifically, the output features of labeled images from the pretrained network combine with corresponding pixel-level annotations to produce class representations according to the mean operation. Then pseudo labels of unlabeled images are generated by calculating the distances between unlabeled feature vectors and each class representation. To further improve the quality of pseudo labels, we adopt a series of operations to optimize pseudo labels. A more accurate segmentation network is obtained by expanding the training dataset and adjusting the contributions between supervised and unsupervised loss. Besides, the novel random patch based on prior locations is introduced for unlabeled images in the training procedure. Extensive experiments show our method has achieved more competitive results compared with other semi-supervised methods when fewer labeled slices of LiTS dataset are available.