Automated bidding is central to modern digital advertising. Early rule-based methods lacked adaptability, while subsequent Reinforcement Learning approaches modeled bidding as a Markov Decision Process but struggled with long-term dependencies. Recent generative models show promise, yet they lack explicit mechanisms to balance exploration and safety, relying solely on action perturbations or trajectory guidance without a safety fallback. This results in inefficient exploration and elevated financial risk for advertising platforms. To address this gap, we propose GUIDE (Generative Auto-Bidding with Unified Modeling and Exploration), a framework that synergistically integrates directed exploration with a safe fallback mechanism. GUIDE employs a Decision Transformer (DT) to jointly model historical bidding actions and environmental state transitions. A Q-value module guides the DT's exploration via regularization constraints, while an Inverse Dynamics Module (IDM) leverages DT-predicted future states to infer robust, behaviorally consistent actions as a safe policy fallback. The Q-value module then adaptively selects the final action between these two options, balancing exploration and safety. Together, these components form an integrated "explore-safeguard-select" pipeline that unifies efficiency and safety. We conduct extensive experiments on public datasets, in simulated auction environments, and through large-scale online deployment on Taobao, a leading Chinese advertising platform. Results show GUIDE consistently outperforms state-of-the-art baselines across all scenarios. In real-world deployment, GUIDE achieves notable gains: +4.10% ad GMV, +1.40% ad clicks, +1.66% ad cost, and +3.52% ad ROI, demonstrating its effectiveness and strong industrial applicability.